Topical formulation raw material
Silver Sulfadiazine is a silver-containing sulfonamide antimicrobial used in topical preparations in specialist topical formulation contexts under applicable regulatory requirements. It is commonly referenced in 1% topical cream formulation contexts and may also be used in dressings and other topical systems. USP defines Silver Sulfadiazine as containing 98.0% to 102.0% of silver sulfadiazine on the dried basis.
Silver Sulfadiazine is a silver-containing sulfonamide antimicrobial used in topical preparations in specialist topical formulation contexts under applicable regulatory requirements. It is commonly referenced in 1% topical cream formulation contexts and may also be used in dressings and other topical systems. USP defines Silver Sulfadiazine as containing 98.0% to 102.0% of silver sulfadiazine on the dried basis.
In veterinary regulated product use, topical silver sulfadiazine is used in companion animals for burns, wounds, and selected skin infections, including use in dogs, cats, and exotic pets under veterinary supervision.
Supply context
BHM Chemicals is a supplier of high quality USP grade Silver Sulfadiazine with tested silver content of 29.3% to 30.5%. This silver content range is aligned with the USP monograph specification for Silver Sulfadiazine.
Minimum order quantity: 5 kg
Silver Sulfadiazine has long been used in burn care because of its broad topical antimicrobial activity and established role in infection prevention. It is particularly valued in the management of burn wounds, where controlling microbial colonization is essential to reducing the risk of wound sepsis. Its continued use in human and veterinary topical formulations reflects its practical importance in wound-care applications.
Silver Sulfadiazine is active against a wide range of burn-related pathogens, including gram-positive and gram-negative bacteria, and it also shows activity against some yeasts. It is recognized for activity against organisms such as Pseudomonas aeruginosa, which is an important pathogen in burn wound infections.
The antimicrobial activity of Silver Sulfadiazine is linked mainly to the action of silver ions at the wound surface. Its activity is primarily topical, which makes it suitable for local application in burn and wound management.
According to USP, Silver Sulfadiazine contains 98.0% to 102.0% of silver sulfadiazine on the dried basis, and the content of silver is specified at 29.3% to 30.5%. These parameters are important for manufacturers requiring consistent pharmacopoeial quality.
Silver Sulfadiazine is primarily used in the prevention and management of infection in partial-thickness and full-thickness burns. It is widely used in specialist topical formulation systems because it requires specification, documentation and regulatory assessment in specialist topical formulation systems.
The substance is used in creams, ointments, and dressings intended for external application. Common formulation references include 1% topical cream systems and other external-use formats.
In veterinary regulated product use, Silver Sulfadiazine is used topically in companion animals for burns, wounds, and skin infections. It is commonly supplied as a cream for direct application to the affected area under veterinary guidance.
Silver Sulfadiazine is intended for topical external use. Care should be taken to avoid contact with the eyes and mucosal surfaces. In regulated use, it should be applied with appropriate hygiene and in accordance with the finished-product instructions. As with other sulfonamide-related products, professional use requires attention to contraindications, hypersensitivity risk, and user-specific precautions.
Silver Sulfadiazine USP is an established topical antimicrobial ingredient used primarily in burn care and related wound-management applications. Its broad antimicrobial activity, defined USP quality standard, and long history of use in both human and veterinary topical formulations make it an important raw material for manufacturers of burn-care and wound-care products.
BHM Chemicals
| Parameter | Specification |
|---|---|
| CAS No. | 22199-08-2 |
| Other names | Silver Sulfadiazine |
| Characteristics | White or almost white crystalline powder. |
| Assay (Content) | 98.0% to 102.0% (dried basis) |
| Identification | Conforms to USP tests |
| Nitrate | Not more than 0.1% |
| Sulfanilic acid | Not more than 0.3% |
| Sufanilamide | Not more than 0.1% |
| Sulfaguanidine | Not more than 0.1% |
| 2-Aminopyrimidine | Not more than 0.3% |
| Acetylsulfadiazine | Not more than 0.2% |
| Specified unidentified impurity | Not more than 0.15% |
| Individual unspecified impurity | Not more than 0.1% |
| Total Impurities | Not more than 0.5% |
| Loss on drying | Not more than 0.5% |
| Silver content | 29.3% to 30.5% |
Full documentation is available on request. Product suitability should be assessed by the customer for the intended application.
Documentation and enquiry
info@bhm-chemicals.com - +48 (0) 519 702 757
Short answers to common B2B enquiry questions.
Yes. Send the product name, CAS number, grade or specification and we will review the B2B enquiry.
Include Silver Sulphadiazine USP, CAS number, required grade, quantity, destination market and documentation needs.
We can coordinate product specification and documentation where available for the specific requirement.
Professional customers from pharmaceutical, cosmetic, food, feed, nutritional or broader chemical sectors may contact us.
The customer confirms suitability against the specification, documentation, regulatory requirements and intended application.