Ronidazole BPV


VETERINARY ACTIVE INGREDIENT


CAS no. 7681-76-7


Ronidazole is a veterinary active ingredient with an antiprotozoal, antimicrobial and antiparasitic properties.


Ronidazole is used in medications for treatment of tritrichomonas infections in pet birds, cats and dogs. It is also ingredient in preparation for swine dysentery, histomoniasis, as well as hexamitosis, giardia, and cochlosoma in all aviary birds and pigeons.


BHM Chemicals is a supplier of high quality BPV grade Ronidazole suitable for use in veterinary applications. 


Minimum order quantity: 5kg

Ronidazole, a potent antibiotic belonging to the nitroimidazole class, serves as a critical therapeutic option primarily in veterinary medicine. 


Historical Background

Initially synthesized for its antimicrobial properties, ronidazole gained recognition in the veterinary world due to its effectiveness against protozoa, specifically in treating trichomoniasis in pigeons and certain infections in cats.


Properties

  1. Antiprotozoal Activity: Ronidazole is known for its ability to target and eliminate protozoa, particularly Trichomonas and Giardia species, common causes of infections in cats and birds.

  2. Mode of Action: It works by disrupting the DNA and RNA synthesis within the protozoal cells, leading to their destruction.

  3. Oral Administration: Typically administered orally, ronidazole is available in various formulations, including tablets and suspensions, for ease of use in veterinary settings.


Uses

Ronidazole finds primary application in veterinary medicine, specifically for the treatment of protozoal infections:

  1. Cats:

    • Giardiasis and Tritrichomonas Foetus Infections: Ronidazole is utilized to address gastrointestinal infections caused by Giardia and Tritrichomonas foetus in cats, aiding in symptom alleviation and eradication of the causative organisms.
  2. Birds (Pigeons):

    • Trichomoniasis: Pigeons often suffer from trichomoniasis, a protozoal infection affecting the upper digestive tract. Ronidazole is an effective treatment in eliminating Trichomonas gallinae, the causative agent.


Benefits

  1. Effective Treatment: Ronidazole has demonstrated efficacy in treating protozoal infections in cats and birds, leading to symptom relief and eradication of the pathogens.

  2. Convenience: The oral administration and various formulations of ronidazole contribute to its ease of use in veterinary practices.

  3. Reduced Spread of Infections: By effectively treating infections in animals, ronidazole aids in preventing the spread of protozoal diseases within populations.


    Ronidazole stands as a crucial tool in the veterinary arsenal for combating protozoal infections in cats and birds. Its efficacy, convenience of administration, and ability to address specific infections make it a valuable option in the treatment of these conditions. However, the use of ronidazole should always be under the guidance of a qualified veterinarian to ensure appropriate dosage, safety, and effectiveness in treating the targeted infections.


    References

    1. Barrs V.R., Martin P., Beatty J.A. (2010) Antiprotozoal treatment for feline giardiasis. Journal of Feline Medicine and Surgery, 12(3), 170-175.
    2. Bojanic K., Stokovic I., Toncic J., Kmetic I., Hohsteter M., Cvetnic Z., Samardzija M. (2006) The efficacy of ronidazole in the treatment of pigeon trichomoniasis. Veterinary Research Communications, 30(3), 279-285.

    PRODUCT SPECIFICATION


    CHARACTERISTICS         

      

     


    Content (Assay)

    Identification

    Colour of solution

     

    (1-Methyl-5-nitroimidazol-2-yl)methanol

    Water content

    Sulphated ash

    Melting point

      

    HAZARDOUS IDENTIFICATION


    STORAGE




    A white to yellowish brown powder, odourless or almost odourless. Slightly  soluble in water , in chloroform and in ethanol, very slightly soluble in  ether.           


    98.5% to 101.0% of C6H8N4O4

    Conforms to BPV (BP) tests

    As per BPV test: A 0.5% w/v solution in methanol is not more intensely coloured than reference  solution Y6

    Conforms to BPV (BP) test

    Maximum 0.5%

    Maximum 0.1%

    About 167oC


    Non-hazardous chemicals


    Keep container tightly closed in a cool and dry place and protected from light. Protect from contamination by foreign substances.


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